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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000735222 2-4-BORONOPHENYLAC 250MG
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Frontier Specialty Chemicals 25G 2-AMINO-5-BROMOPYRIMIDINE
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2-Amino-5-bromopyrimidine; CAS No: 7752-82-1
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Apexbio Technology LLC ACY-241 1316215-12-9 5mg
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ACY-241 (CAS 1316215-12-9) is a selective orally bioavailable inhibitor of histone deacetylase 6 (HDAC6) an enzyme that removes acetyl groups from -N-acetyl lysine residues on histones thus modulating chromatin structure and gene expression In preclinical studies ACY-241 demonstrated synergistic induction of apoptosis in multiple myeloma and mantle cell lymphoma cells when combined with immunomodulatory agents such as lenalidomide or pomalidomide accompanied by reduced MYC and IRF4 expression In solid tumor models co-administration with paclitaxel enhanced mitotic defects and led to dose-dependent hyperacetylation of -tubulin These findings support ACY-241 as a tool compound for investigating HDAC6 modulation in hematological and solid malignancies
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Chemscene ChemScene | 4,5,6-Trichloropyrimidine | 5G | CS-W017036 | 0.98 | 1780-27-4| MFCD08458457 | 183.43
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ChemScene | 4,5,6-Trichloropyrimidine | 5G | CS-W017036 | 0.98 | 1780-27-4| MFCD08458457 | 183.43
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Medchemexpress LLC Deracoxib | 169590-41-4 | 397.37 | 250 MG
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Deracoxib | 169590-41-4 | 397.37 | 250 MG
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Ambeed AMBEED
5000884084 ETHYL 44-DIFLUOROCYCLOHE 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382653 POMALIDOMIDE 4 -ALKY 250MG
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Medchemexpress LLC Ethyl 2-chloropyrimidine-5-carboxylate | 89793-12-4 | 186.60 | 10 G
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Ethyl 2-chloropyrimidine-5-carboxylate is a chemical compound commonly used for synthesis in laboratory research. This white to yellow solid is provided for research purposes only.
- Molecular formula: C7H7ClN2O2
- Molecular weight: 186.60
- CAS number: 89793-12-4
- Purity: 99.7%
- Identified uses: Laboratory chemicals, manufacture of substances
- Appearance: Solid, white to yellow
- Melting/freezing point: 52-60°C
- Boiling point: 314.2°C at 760 mmHg
- Stable under recommended storage conditions
- Storage: 4°C, sealed storage, away from moisture; in solvent: -80°C, 6 months; -20°C, 1 month
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Medchemexpress LLC Quinocetone | 81810-66-4 | MFCD09753267 | 98.0% | 306.32 g/mol | C18H14N2O3 | 250MG
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Quinocetone is a synthetic antibacterial compound used as an orally active animal feed additive to improve growth performance and control intestinal infections in livestock and poultry. Supplied for research and analytical purposes, it is provided as a solid or as a DMSO solution and is commonly used in veterinary studies and residue analysis.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382345 AHR ANTAGONIST 2 250MG
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![Medchemexpress LLC 3-azaspiro[5.5]undecane hydrochloride | 1125-01-5 | MFCD02093801 | 97.0% | 189.73 g·mol⁻¹ | C10H20ClN | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241179.png-250.jpg)
Medchemexpress LLC 3-azaspiro[5.5]undecane hydrochloride | 1125-01-5 | MFCD02093801 | 97.0% | 189.73 g·mol⁻¹ | C10H20ClN | 250 MG
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3-Azaspiro[5.5]undecane hydrochloride is a spirocyclic small molecule supplied as the hydrochloride salt for research use. It is a white to off-white solid with reported purity ≥97% and molecular weight 189.73 g·mol⁻¹. The compound has been reported to inhibit the wild-type influenza A virus M2 proton channel (A/M2) with an IC50 of 1 μM (two-electrode patch clamp assay).
- Inhibits influenza A virus M2 proton channel (IC50 1 μM).
- Supplied as a stable white to off-white solid.
- Chemical formula C10H20ClN and molecular weight 189.73 g·mol⁻¹.
- High reported purity (≥97%) suitable for research applications.
- Available in multiple laboratory pack sizes for flexibility.
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![eMolecules 1111638-52-8 | 2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone | Broadpharm | MFCD18157747 | 424.490 | C20H16N4O3S2 | 0.000 | CSc1nccc(CC(=O)c2cnc3n(ccc3c2)S(=O)(=O)c2ccccc2)n1 | 25mg | 311074407](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502466569.JPG-250.jpg)
eMolecules 1111638-52-8 | 2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone | Broadpharm | MFCD18157747 | 424.490 | C20H16N4O3S2 | 0.000 | CSc1nccc(CC(=O)c2cnc3n(ccc3c2)S(=O)(=O)c2ccccc2)n1 | 25mg | 311074407
2-[2-(Methylthio)pyrimidin-4-yl]-1-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]ethanone | Broadpharm | 1111638-52-8 | MFCD18157747 | 424.490 | C20H16N4O3S2 | 0.000 | CSc1nccc(CC(=O)c2cnc3n(ccc3c2)S(=O)(=O)c2ccccc2)n1 | 25mg | 311074407
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Aobchem AOBCHEM
5000874367 3-METHYL-5-PROPIONYLTHIOPHENE-
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eMolecules 85386-14-7 | Ethyl 2-phenylpyrimidine-5-carboxylate | ChemScene | MFCD09863207 | 228.251 | C13H12N2O2 | 98.000 | CCOC(=O)c1cnc(nc1)-c1ccccc1 | 250mg | 632287016
Ethyl 2-phenylpyrimidine-5-carboxylate | ChemScene | 85386-14-7 | MFCD09863207 | 228.251 | C13H12N2O2 | 98.000 | CCOC(=O)c1cnc(nc1)-c1ccccc1 | 250mg | 632287016
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Medchemexpress LLC 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380) | 1627138-52-6 | 99.9% | 494.53 g/mol | C23H25F3N4O3S | 50MG
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ML380 is a potent, subtype-selective, brain-penetrant positive allosteric modulator (PAM) of the M5 muscarinic acetylcholine receptor (mAChR), reported with EC50 ≈190 nM (human) and ≈610 nM (rat). It is supplied for preclinical pharmacology and neuroscience research; molecular formula C23H25F3N4O3S, molecular weight 494.53 g/mol.
- Potent M5 positive allosteric modulator (EC50 ≈190 nM human).
- Moderate selectivity versus M1 and M3 subtypes.
- Brain-penetrant profile suitable for CNS studies.
- High purity (99.87%) for reliable experimental use.
- Soluble in DMSO at 100 mg/mL for formulation and dosing.
- Available in multiple vial sizes to support in vitro and in vivo studies.
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